Breast diseases · Benign breast diseases

Phyllodes Tumor (Cystosarcoma Phyllodes)

Phyllodes Tumor (Cystosarcoma Phyllodes)

PHYLLODES TUMOR

Phyllodes tumor of the breast is a rare fibroepithelial breast tumor. Its incidence is 2-3%. Phyllodes tumors are classified as benign, borderline or malignant. It is often benign and rarely appears in its malignant form. Although it is most often seen at ages 35-55, malignant phyllodes tumors are seen at older ages.

Since a phyllodes tumor has a much higher growth rate than fibroadenomas, it begins to take up space inside the breast at an early stage. Imaging methods such as breast ultrasound, mammography and breast MRI, and in many cases biopsy, are insufficient in the differential diagnosis. The definitive diagnosis is made by pathological evaluation after the mass has been completely removed.

The treatment of phyllodes tumors is surgical removal of the mass together with at least 1 cm of surrounding breast tissue. Regional recurrence in the breast often occurs. In giant phyllodes tumors, removal of the whole breast may be healthier. In this case the breast is rebuilt with a silicone prosthesis. There is generally no spread to the armpit lymph nodes; surgical intervention for them is not recommended.

Benign phyllodes tumors are treated surgically, while in malignant phyllodes tumors radiotherapy to the chest wall may be applied after surgery. Close follow-up after surgery is important for regional recurrence.

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Frequently asked questions

Your questions, answered.

The most common questions about Phyllodes Tumor (Cystosarcoma Phyllodes), with short answers.

What is a phyllodes tumor?

A phyllodes tumor (cystosarcoma phyllodes) is a rare fibroepithelial breast tumor with an incidence of 2-3 percent. It is classified as benign, borderline or malignant and is most often benign.

At what age does a phyllodes tumor occur?

It is most common between ages 35 and 55; malignant phyllodes tumor is seen at older ages.

What is the difference between a phyllodes tumor and a fibroadenoma?

A phyllodes tumor grows much faster than a fibroadenoma and starts taking up space in the breast early.

How is a phyllodes tumor diagnosed?

Imaging such as breast ultrasound, mammography and breast MRI, and often biopsy, are insufficient for differential diagnosis. The definitive diagnosis is made by pathological evaluation after the whole mass is removed.

How is a phyllodes tumor treated?

Treatment is surgical removal of the mass with at least 1 cm of surrounding breast tissue. In giant phyllodes tumors removing the whole breast may be healthier; the breast is then rebuilt with a silicone prosthesis. In malignant forms radiotherapy to the chest wall may be given after surgery.

Does a phyllodes tumor recur?

Local recurrence in the breast is frequent. Close follow-up for local recurrence after surgery is therefore important.

Are armpit lymph nodes removed in phyllodes tumor?

Spread to armpit lymph nodes does not usually occur, so surgery for them is not recommended.

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