Breast diseases · Benign breast diseases

Intraductal Papillomas

Intraductal Papillomas

Intraductal Papilloma of the Breast

It is a tumor that occurs as a result of some of the cells lining the inside of the milk ducts growing faster than the other cells. A single one occurs especially inside the milk ducts located behind the nipple. Multiple tumors are seen in the more outer regions of the breast. Intraductal papilloma is generally considered a benign epithelial tumor, but when it is accompanied by atypical hyperplasia it has the potential to be malignant.
The main complaint is spontaneous bloody nipple discharge in women between the ages of 30 and 50. Since an intraductal papilloma is a small tumor of 3-7 mm inside the milk duct, breast ultrasound and mammography are insufficient for detection. Additional auxiliary diagnostic methods such as breast MRI, ductography and ductoscopy are used. Pathological evaluation is important for the differential diagnosis; a smear can be taken from the nipple discharge and a biopsy can be taken from the tumor.
The treatment of a benign intraductal papilloma with persistent nipple discharge is surgical removal together with the milk duct in which the tumor is located. If atypical hyperplasia is present, a wider surgical excision is recommended.

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Frequently asked questions

Your questions, answered.

The most common questions about Intraductal Papillomas, with short answers.

What is an intraductal papilloma?

It is a tumor formed when some of the cells lining the milk ducts grow faster than others. It occurs singly in the milk ducts behind the nipple; multiple tumors are seen in the outer areas of the breast.

Is an intraductal papilloma cancer?

An intraductal papilloma is generally considered a benign epithelial tumor. When it occurs with atypical hyperplasia, however, it has the potential to become malignant.

What is the symptom of an intraductal papilloma?

The main complaint is spontaneous bloody nipple discharge in women aged 30-50.

How is an intraductal papilloma diagnosed?

Because the tumor is a small structure of 3-7 mm inside the milk duct, breast ultrasound and mammography may be insufficient. Breast MRI, ductography and ductoscopy are helpful tests. Pathological evaluation is important; a smear of the discharge and a biopsy of the tumor can be done.

How is an intraductal papilloma treated?

Treatment of a benign intraductal papilloma with persistent nipple discharge is surgical removal together with the milk duct containing the tumor.

Does treatment change if there is atypical hyperplasia?

Yes. If atypical hyperplasia is present, a wider surgical excision is recommended.

What is the most common cause of bloody nipple discharge?

Intraductal papilloma accounts for about 45 percent of bloody nipple discharge. See the nipple discharge page for details.

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